Article
Single nucleotide repeat analysis of B. anthracis isolates in Canada through comparison of pyrosequencing and Sanger sequencing.
Veterinary microbiology - 14 Mar 2014
Hahn Kristen R, Janzen Timothy W, Thomas Matthew C, Shields Michael J, Goji Noriko, Valle Edith, Amoako Kingsley K
Abstract excerpt
Several technology platforms have been developed to resolve the phylogenetic placement of B. anthracis. However, these methods lack the resolution to identify differences between closely related strains within an outbreak due to the highly clonal nature of B. anthracis. Single Nucleotide Repeats (SNRs) are a type of rapidly evolving genetic marker that can be used to track epidemiological distribution in the...
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