Article
Multiple-locus variable-number tandem repeat analysis reveals genetic relationships within Bacillus anthracis.
Journal of bacteriology - 1 May 2000
Keim P, Price L B, Klevytska A M, Smith K L, Schupp J M, Okinaka R, Jackson P J, Hugh-Jones M E
Abstract excerpt
Bacillus anthracis is one of the most genetically homogeneous pathogens described, making strain discrimination particularly difficult. In this paper, we present a novel molecular typing system based on rapidly evolving variable-number tandem repeat (VNTR) loci. Multiple-locus VNTR analysis (MLVA) uses the combined power of multiple alleles at several marker loci. In our system, fluorescently labeled PCR primers...
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