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Article

Ionic dysregulatory phenotyping of pathologic retinal thinning with manganese-enhanced MRI.

Investigative ophthalmology & visual science - 1 Jul 2008

Berkowitz Bruce A, Gradianu Marius, Schafer Stephen, Jin Ying, Porchia Andre, Iezzi Raymond, Roberts Robin

Abstract excerpt

PURPOSE: To test the hypothesis that manganese-enhanced MRI (MEMRI) provides a sensitive and robust measure of an important retinal ionic dysregulatory phenotype in pathologic retinal thinning. METHODS: Four hours after intraperitoneal MnCl(2) injection, high-resolution MEMRI data were collected from overnight dark-adapted male control Sprague-Dawley and albino Royal College of Surgeons rats before (at...

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Identifiers

PMID: 18362105
DOI: 10.1167/iovs.08-1720
PMCID: PMC2517149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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