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Article

X-ray fluorescence microscopic measurement of elemental distribution in the mouse retina with age.

Metallomics : integrated biometal science - 1 Oct 2016

Grubman Alexandra, Guennel Philipp, Vessey Kirstan A, Jones Michael W M, James Simon A, de Jonge Martin D, White Anthony R, Fletcher Erica L

Abstract excerpt

The biologically important metals such as zinc, copper and iron play key roles in retinal function, yet no study has mapped the spatio-temporal distribution of retinal biometals in healthy or diseased retina. We investigated a natural mouse model of retinal degeneration, the Cln6nclf mouse. As dysfunctional metabolism of biometals is observed in the brains of these animals and deregulated metal homeostasis has...

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Identifiers

PMID: 27481440
DOI: 10.1039/c6mt00055j

Genes

RPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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