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Article

Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer.

Cancer - 1 Jun 2008

Ye Yuanqing, Yang Hushan, Grossman H Barton, Dinney Colin, Wu Xifeng, Gu Jian

Abstract excerpt

BACKGROUND: Cell cycle checkpoint regulation is crucial for the prevention of carcinogenesis in mammalian cells. METHODS: To test the hypothesis that common sequence variants in the cell cycle control pathway may affect bladder cancer susceptibility, the effects of a panel of 10 potential functional single nucleotide polymorphisms (SNPs) from 7 cell cycle control genes, P53, P21, P27, CDK4, CDK6, CCND1, and...

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Source

Identifiers

PMID: 18361427
DOI: 10.1002/cncr.23472

Genes

CCND1
CDK4
CDK6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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