Article
A single-nucleotide polymorphism in C-type natriuretic peptide gene may be associated with hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Sept 2002
Ono Koh, Mannami Toshifumi, Baba Shunroku, Tomoike Hitonobu, Suga Sin-ichi, Iwai Naoharu
Abstract excerpt
We conducted an association study between genetic variants of C-type natriuretic peptide gene (CNP) and hypertension in a Japanese population. We found four genetic variants, two in the promoter region, one missense mutation, and one in the 3'-untranslated region (3'-UTR), and genotyped all four variants in 2,006 subjects recruited from the Suita study. One of the variants, G2628A in 3'-UTR, was found to be...
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