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Article

Cleavage of normal and pathological forms of alpha-synuclein by neurosin in vitro.

Neuroscience letters - 2 May 2008

Kasai Takashi, Tokuda Takahiko, Yamaguchi Nozomi, Watanabe Yoshihisa, Kametani Fuyuki, Nakagawa Masanori, Mizuno Toshiki

Abstract excerpt

Neurosin is one of the serine proteases predominantly expressed in the central nervous system. Neurosin is presumed to play an important role in the degradation of alpha-synuclein (alpha-syn), since a previous study showed that neurosin degrades alpha-syn, inhibits polymerization of alpha-syn in vitro, and exists in Lewy bodies. However, the details of alpha-syn degradation by neurosin are little known. We...

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Identifiers

PMID: 18358605
DOI: 10.1016/j.neulet.2008.02.057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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