Article
Investigation into the ability of SNP chipsets and microsatellites to detect association with a disease locus.
Annals of human genetics - 1 Jul 2008
Curtis D, Vine A E, Knight J
Abstract excerpt
We wished to investigate the ability of different SNP chipsets to detect association with a disease and to investigate the linkage disequilibrium (LD) relationships between microsatellites and nearby SNPs in order to assess their potential usefulness to detect association. SNP genotypes were obtained from HapMap and microsatellite genotypes from CEPH. 5000 SNPs were simulated as disease genes which increased...
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