Article
Application of genomewide SNP arrays for detection of simulated susceptibility loci.
Human mutation - 1 Jun 2005
Kulle Bettina, Schirmer Markus, Toliat Mohammad R, Suk Anita, Becker Christian, Tzvetkov Mladen Vassilev, Brockmöller Jürgen, Bickeböller Heike, Hasenfuss Gerd, Nürnberg Peter, Wojnowski Leszek
Abstract excerpt
The prospect of SNP-based genomewide association analysis has been extensively discussed, but practical experiences remain limited. We performed an association study using a recently developed array of 11,555 SNPs distributed throughout the human genome. A total of 104 DNA samples were hybridized to these chips with an average call rate of 97% (range 85.3-98.6%). The resulting genomewide scans were applied to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
