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Article

Inhibition of ICAM2 induces radiosensitisation in oral squamous cell carcinoma cells

18 Mar 2008

Abstract excerpt

We recently identified genes and molecular pathways related to radioresistance of oral squamous cell carcinoma (OSCC) using Affymetrix GeneChip. The current study focused on the association between one of the target genes, intercellular adhesion molecule 2 (ICAM2), and resistance to X-ray irradiation in OSCC cells, and evaluated the antitumor efficacy of combining ICAM2 small interfering RNA (siRNA) and X-ray...

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PMID: 18349842
DOI: 10.1038/sj.bjc.6604290

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