Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endothelial cell migration in stable gradients of vascular endothelial growth factor A and fibroblast growth factor 2: effects on chemotaxis and chemokinesis.

The Journal of biological chemistry - 16 May 2008

Barkefors Irmeli, Le Jan Sébastien, Jakobsson Lars, Hejll Eduar, Carlson Gustav, Johansson Henrik, Jarvius Jonas, Park Jeong Won, Li Jeon Noo, Kreuger Johan

Abstract excerpt

Gradients of secreted signaling proteins guide growing blood vessels during both normal and pathological angiogenesis. However, the mechanisms by which endothelial cells integrate and respond to graded distributions of chemotactic factors are still poorly understood. We have in this study investigated endothelial cell migration in response to hill-shaped gradients of vascular endothelial growth factor A (VEGFA)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arteries
Share to Chemotaxis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Fibroblast Growth Factor 2

Share to Intercellular Signaling Peptides and Proteins

Share to Microscopy

Share to Protein Isoforms

Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 18347025
DOI: 10.1074/jbc.M704917200

Genes

FGF2
MCC
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endothelial cell migration in stable gradients of vascular endothelial growth factor A and fibroblast growth factor 2: effects on chemotaxis and chemokinesis.PMID 18347025Read ↗

3D Printed Multiplexed Competitive Migration Assays with Spatially Programmable Release SourcesSemantic proximity Read ↗

Tunable Laminar Perfusion Coordinates Endothelial and Perivascular Remodeling in Angiogenic Vasculature-on-ChipSemantic proximity Read ↗

A novel in vitro angiogenesis model based on a microfluidic deviceSemantic proximity Read ↗

Mechanism of a flow-gated angiogenesis switch: early signaling events at cell-matrix and cell-cell junctions.Semantic proximity Read ↗

Analysis of CCR7 mediated T cell transfectant migration using a microfluidic gradient generator.Semantic proximity Read ↗

New View on Endothelial Cell Migration: Switching Modes of Migration Based on Matrix Composition.Semantic proximity Read ↗

Oxygen-induced cell migration and on-line monitoring biomarkers modulation of cervical cancers on a microfluidic systemSemantic proximity Read ↗

Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels.Semantic proximity Read ↗

A Worldwide Competition to Compare the Speed and Chemotactic Accuracy of Neutrophil-Like CellsSemantic proximity Read ↗

Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs.Semantic proximity Read ↗

Physical constraints on accuracy and persistence during breast cancer cell chemotaxisSemantic proximity Read ↗

A Bistable Mechanism Mediated by Integrins Controls Mechanotaxis of LeukocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.