Article
Analysis of CCR7 mediated T cell transfectant migration using a microfluidic gradient generator.
Journal of immunological methods - 1 Apr 2015
Wu Xun, Wu Jiandong, Li Hongzhao, Legler Daniel F, Marshall Aaron J, Lin Francis
Abstract excerpt
T lymphocyte migration is crucial for adaptive immunity. Manipulation of signaling molecules controlling cell migration combined with in-vitro cell migration analysis provides a powerful research approach. Microfluidic devices, which can precisely configure chemoattractant gradients and allow quantitative single cell analysis, have been increasingly applied to cell migration and chemotaxis studies. However, there...
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