Article
Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels.
Biomaterials - 1 Aug 2010
Price Gavrielle M, Wong Keith H K, Truslow James G, Leung Alexander D, Acharya Chitrangada, Tien Joe
Abstract excerpt
This work examines how mechanical signals affect the barrier function and stability of engineered human microvessels in microfluidic type I collagen gels. Constructs that were exposed to chronic low flow displayed high permeabilities to bovine serum albumin and 10 kDa dextran, numerous focal leak...
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