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Article

TNFalpha in patients with end-stage heart failure on medical therapy or supported by a left ventricular assist device.

Transplant immunology - 1 Apr 2008

Bruggink A H, van Oosterhout M F M, De Jonge N, Gmelig-Meyling F H J, De Weger R A

Abstract excerpt

BACKGROUND: In the heart elevated levels of TNFalpha can cause lethal heart failure, like Dilated Cardiomyopathy (DCM). The level of TNFalpha production is in part determined by promoter gene polymorphisms. We investigated whether the TNFalpha promoter gene polymorphism is in this way involved in the outcome of end-stage heart failure and predicts whether patients require left ventricular assist device (LVAD)...

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Source

Identifiers

PMID: 18346639
DOI: 10.1016/j.trim.2008.01.001

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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