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[Carriage of A Allele of Polymorphic Marker G(-238)A of TNF Gene Is Associated With Unfavorable Prognosis in Patients With Chronic Systolic Heart Failure].

Kardiologiia - 1 Jan 2015

Gerasimova O N, Sigalovich E Yu, Dankovtseva E N, Nakonechnikov S N, Nikitin A G, Ivanova Z V, Masenko V P, Nosikov V V, Zateyshchikov D A

Abstract excerpt

AIM: to elucidate association between polymorphic markers of interleukin-6 (Il-6) and tumor necrosis factor (TNF) genes and unfavorable outcomes in patients with chronic heart failure (CHF). MATERIAL AND METHODS: We determined levels of TNF and Il-6 and genotypes of polymorphic markers G(-238)A of TNF gene (rs361525) and G(--174)C of IL-6 gene (rs1800795) in 151 patients (mean age 64.5 years) hospitalized because...

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PMID: 26922818

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TNF

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Source receipt: pubmed, retrieved 7 Sept 2026.

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