Article
Tumour necrosis factor-alpha promoter polymorphism and its association with viral dilated cardiomyopathy in Indian population: a pilot study.
Indian journal of medical microbiology - 1 Jan 2000
Mishra B, Sharma M, Sarkar S, Bahl A, Saikia U N, Ratho R K
Abstract excerpt
PURPOSE: Tumour necrosis factor-α (TNF-α), a pro-inflammatory cytokine has been implicated in the pathophysiology of several viral infections. TNF-α promoter gene polymorphism is thus believed to play the modulating role in this disease pathogenesis. Several studies have shown the increased level of TNF-α in dilated cardiomyopathy (DCM). However, the role of the TNF-α promoter polymorphism is yet to be delineated...
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