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Article

A common SNP haplotype provides molecular proof of a founder effect of Huntington disease linking two South African populations.

European journal of human genetics : EJHG - 1 May 2007

Scholefield Janine, Greenberg Jacquie

Abstract excerpt

This study involved the detailed investigation of the region surrounding the huntingtin gene in families with a history of Huntington Disease (HD) in South Africa. The primary aim was to investigate the origins of the HD mutation in South Africa by constructing a single-nucleotide polymorphism (SNP) haplotype around the HD gene and to determine how many haplotypes there are in two different South African...

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PMID: 17327878
DOI: 10.1038/sj.ejhg.5201796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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