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Article

Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study.

The Lancet. Oncology - 1 Apr 2008

Moore Lee E, Pfeiffer Ruth M, Poscablo Cristina, Real Francisco X, Kogevinas Manolis, Silverman Debra, García-Closas Reina, Chanock Stephen, Tardón Adonina, Serra Consol, Carrato Alfredo, Dosemeci Mustafa, García-Closas Montserrat, Esteller Manel, Fraga Mario, Rothman Nathaniel, Malats Núria

Abstract excerpt

BACKGROUND: DNA hypomethylation has been suggested to cause genomic instability and increase cancer risk. We aimed to test the hypothesis that DNA hypomethylation is associated with increased risk of bladder cancer. METHODS: We measured cytosine methylation (5-mC) content in genomic DNA from bloo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18339581
DOI: 10.1016/S1470-2045(08)70038-X
PMCID: PMC2601672

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18339581-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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