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Article

Genomic DNA Hypomethylation and Risk of Renal Cell Carcinoma: A Case-Control Study.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2016

Mendoza-Pérez Julia, Gu Jian, Herrera Luis A, Tannir Nizar M, Matin Surena F, Karam Jose A, Huang Maosheng, Chang David W, Wood Christopher G, Wu Xifeng

Abstract excerpt

PURPOSE: Genomic DNA hypomethylation is a hallmark of most cancer genomes, promoting genomic instability and cell transformation. In the present study, we sought to determine whether global DNA methylation in peripheral blood is associated with risk of renal cell carcinoma (RCC). EXPERIMENTAL DESIGN: A retrospective case-control study consisting of 889 RCC cases and an equal number of age, gender, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26655847
DOI: 10.1158/1078-0432.CCR-15-0977
PMCID: PMC4834236

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