Article
Investigation of mutations and expression of the FHIT gene in Turkish patients with brain metastases derived from non-small cell lung cancer.
Tumori - 1 Jan 2000
Bekar Ahmet, Ceçener Gülşah, Tunca Berrin, Guler Gulnur, Egeli Unal, Tolunay Sahsine
Abstract excerpt
AIMS AND BACKGROUND: Brain metastases occur in 20-40% of patients with cancer, and their frequency has increased over time. Lung, breast and skin (melanoma) are the most common sources of brain metastases. Recent studies show that several genes such as CD44 and PTEN have roles in the suppression of metastatic growth. Although it has been determined that there is a relationship between the FHIT gene and several...
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