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Article

Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis.

Molecular cancer research : MCR - 1 Mar 2008

Cha Jiyoung Y, Lambert Que T, Reuther Gary W, Der Channing J

Abstract excerpt

We identified the IIIb C2 epithelial cell-specific splice variant of fibroblast growth factor receptor 2 (FGFR2 IIIb C2) receptor tyrosine kinase in a screen for activated oncogenes expressed in T-47D human breast carcinoma cells. We found FGFR2 IIIb C2 expression in breast carcinoma cell lines and, additionally, expression of the mesenchymal-specific FGFR2 IIIc splice variant in invasive breast carcinomas. FGFR2...

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Source

Identifiers

PMID: 18337450
DOI: 10.1158/1541-7786.MCR-07-0187

Genes

FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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