Article
Expression, regulation and function of asporin, a susceptibility gene in common bone and joint diseases.
Current medicinal chemistry - 1 Jan 2008
Ikegawa Shiro
Abstract excerpt
Asporin is an extracellular matrix protein that belongs to the small leucine-rich repeat proteoglycan (SLRP) family of proteins. It is unique among SLRPs in that it lacks a glycosaminoglycan attachment site and contains an asparatic acid (D) repeat at its amino terminus. Its biological role has been unclear, but recent genetic studies have demonstrated association between asporin and various bone and joint...
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