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Article

Expression and Regulation of the Osteoarthritis-associated Protein Asporin

6 Sept 2007

Abstract excerpt

Asporin (ASPN) is a small leucine-rich proteoglycan that is involved in pathological processes of osteoarthritis. Previously, we showed that asporin can inhibit transforming growth factor-beta1 (TGF-beta1)-mediated expression of cartilage matrix genes and chondrogenesis in vitro (Kizawa, H., Kou, I., Iida, A., Sudo, A., Miyamoto, Y., Fukuda, A., Mabuchi, A., Kotani, A., Kawakami, A., Yamamoto, S., Uchida, A.,...

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Identifiers

PMID: 17804408
DOI: 10.1074/jbc.m706262200

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