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Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study.

Pharmacogenetics and genomics - 1 Apr 2008

Donnelly Louise A, Palmer Colin N A, Whitley Adrian L, Lang Chim Choy, Doney Alex S F, Morris Andrew D, Donnan Peter T

Abstract excerpt

BACKGROUND: Apolipoprotein E (APOE) genotypes have been associated with variations in plasma-lipid levels and with response to statins, although the influence of APOE on the response to statins remains controversial, especially in patients with diabetes. We sought to evaluate the association of the APOE genotype with the low-density lipoprotein cholesterol (LDLc)-lowering response to statins, in a large...

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Source

Identifiers

PMID: 18334912
DOI: 10.1097/FPC.0b013e3282f60aad

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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