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Article

Molecular basis for peroxisomal localization of tetrameric carbonyl reductase.

Structure (London, England : 1993) - 1 Mar 2008

Tanaka Nobutada, Aoki Ken-Ichi, Ishikura Shuhei, Nagano Makoto, Imamura Yorishige, Hara Akira, Nakamura Kazuo T

Abstract excerpt

Pig heart peroxisomal carbonyl reductase (PerCR) belongs to the short-chain dehydrogenase/reductase family, and its sequence comprises a C-terminal SRL tripeptide, which is a variant of the type 1 peroxisomal targeting signal (PTS1) Ser-Lys-Leu. PerCR is imported into peroxisomes of HeLa cells when the cells are transfected with vectors expressing the enzyme. However, PerCR does not show specific targeting when...

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Source

Identifiers

PMID: 18334214
DOI: 10.1016/j.str.2007.12.022

Genes

SRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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