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Article

Suitability of tamoxifen-induced mutagenesis for behavioral phenotyping.

Experimental neurology - 1 May 2008

Vogt M A, Chourbaji S, Brandwein C, Dormann C, Sprengel R, Gass P

Abstract excerpt

Tamoxifen-induced mutagenesis via the so-called CreER(T2) fusion enzyme is a key technology for the inducible gene knockout in the adult murine brain. However, it requires a subchronic transient treatment with high doses of the non-selective estrogen receptor antagonist tamoxifen. It has been sho...

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PMID: 18329640
DOI: 10.1016/j.expneurol.2007.12.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18329640-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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