Article
CD45 isoform expression on human neonatal T cells: expression and turnover of CD45 isoforms on neonatal versus adult T cells after activation.
Cellular immunology - 1 Jun 1992
Yamada A, Kaneyuki T, Hara A, Rothstein D M, Yokoyama M M
Abstract excerpt
Neonatal T cells are phenotypically similar to "naive" T cells from adult donors in the CD45 isoform expression. Despite the phenotypic similarity, large differences were found between neonatal and adult T cells when T cells were activated. After activation with PHA, adult CD45RA+ T cells began to express CD45RO and no loss of CD45RA expression had yet occurred at Day 3 post-stimulation. Three days after...
Topics
- Adult
- Age Factors
- Antigens, CD
- Cell Membrane
- Histocompatibility Antigens
- Humans
- Infant, Newborn
- Leukocyte Common Antigens
- Lymphocyte Activation
- Phenotype
- T-Lymphocytes