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SHOREmap v3.0: fast and accurate identification of causal mutations from forward genetic screens.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015

Sun Hequan, Schneeberger Korbinian

Abstract excerpt

Whole-genome resequencing of pools of recombinant mutant genomes allows direct linking of phenotypic traits to causal mutations. Such analysis, called mapping-by-sequencing, combines classical genetic mapping and next-generation sequencing by relying on selection-induced patterns within genome-wide allele frequency (AF) in pooled genomes. Mapping-by-sequencing can be performed with computational tools such as...

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PMID: 25757783
DOI: 10.1007/978-1-4939-2444-8_19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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