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Article

Characterization of the GNAQ promoter and association of increased Gq expression with cardiac hypertrophy in humans.

European heart journal - 1 Apr 2008

Frey Ulrich H, Lieb Wolfgang, Erdmann Jeanette, Savidou Danai, Heusch Gerd, Leineweber Kirsten, Jakob Heinz, Hense Hans-Werner, Löwel Hannelore, Brockmeyer Norbert H, Schunkert Heribert, Siffert Winfried

Abstract excerpt

AIMS: Transgenic mice with cardiac overexpression of Gq develop cardiac hypertrophy, apoptosis, and heart failure. Similar mechanisms may contribute to human left ventricular hypertrophy (LVH). However, mechanisms regulating transcription of the human GNAQ gene encoding the Gq protein are unknown...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to GTP-Binding Protein alpha Subunits, Gq-G11

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Source

Identifiers

PMID: 18326504
DOI: 10.1093/eurheartj/ehm618

Genes

GNAQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18326504-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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