Article
Role of chromosome 3q amplification in lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Mar 2008
Qian Jun, Massion Pierre P
Abstract excerpt
Chromosome abnormalities often correlate with molecular abnormalities and provide a starting point for gene discovery and characterization in the context of a specific disorder. In cancer biology, chromosomal abnormalities carry diagnosis, prognostic, and predictive value of response to treatment. Recently, methodologies such as array comparative genomic hybridization and oligonucleotide microarrays allow...
Topics
- Chromosome Aberrations
- Chromosomes, Human, Pair 3
- Disease Progression
- Gene Amplification
- Genetic Predisposition to Disease
- Humans
- Lung Neoplasms
- Prognosis
