Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using dimensional models of externalizing psychopathology to aid in gene identification.

Archives of general psychiatry - 1 Mar 2008

Dick Danielle M, Aliev Fazil, Wang Jen C, Grucza Richard A, Schuckit Marc, Kuperman Samuel, Kramer John, Hinrichs Anthony, Bertelsen Sarah, Budde John P, Hesselbrock Victor, Porjesz Bernice, Edenberg Howard J, Bierut Laura Jean, Goate Alison

Abstract excerpt

CONTEXT: Twin studies provide compelling evidence that alcohol and drug dependence, childhood conduct disorder, adult antisocial behavior, and disinhibitory personality traits share an underlying genetic liability that contributes to a spectrum of externalizing behaviors. However, this informatio...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Linkage
Share to Mental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Theoretical

Share to Pedigree

Share to Principal Component Analysis

Share to Receptor, Muscarinic M2

Share to Substance-Related Disorders

Share to United States

Source

Identifiers

PMID: 18316677
DOI: 10.1001/archpsyc.65.3.310

Genes

CHRM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18316677-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using dimensional models of externalizing psychopathology to aid in gene identification.PMID 18316677Read ↗

The Genetics of Externalizing Problems.Semantic proximity Read ↗

A Family-Based Genome Wide Association Study of Externalizing Behaviors.Semantic proximity Read ↗

Parsing Genetically Influenced Risk Pathways: Genetic Loci Impact Problematic Alcohol Use Via Externalizing and Specific RiskSemantic proximity Read ↗

A multivariate approach to understanding the genetic overlap between externalizing phenotypes and substance use disorders.Semantic proximity Read ↗

Alcohol-related genes show an enrichment of associations with a persistent externalizing factor.Semantic proximity Read ↗

A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology SpectraSemantic proximity Read ↗

Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.Semantic proximity Read ↗

Associations Between a Genetic Liability Toward Externalizing and Behavioral Outcomes Spanning Toddlerhood Through Early Adulthood in Five Developmental Cohorts.Semantic proximity Read ↗

Identification of Transdiagnostic Childhood Externalizing Pathology Within an Electronic Medical Records Database and Application to the Analysis of Rare Copy Number Variation.Semantic proximity Read ↗

Disentangling differing relationships between internalizing disorders and alcohol use.Semantic proximity Read ↗

Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample.Semantic proximity Read ↗

Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.