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DNA copy number alterations and expression of relevant genes in triple‐negative breast cancer

3 Mar 2008

Abstract excerpt

Triple-negative breast cancer (TNBC) is defined by a lack of expression of estrogen, progesterone, and HER2 receptors, and genetically most of them fall into the basal subgroup of breast cancer. The important issue of TNBC is poorer clinical outcome and absence of effective targeted therapy. In this study, we sought to identify DNA copy number alterations and expression of relevant genes characteristic of TNBC to...

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PMID: 18314908
DOI: 10.1002/gcc.20550

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