Article
Comprehensive analysis of tagging sequence variants in DTNBP1 shows no association with schizophrenia or with its composite neurocognitive endophenotypes.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008
Peters Kirsten, Wiltshire Steven, Henders Anjali K, Dragović Milan, Badcock Johanna C, Chandler David, Howell Sarah, Ellis Chris, Bouwer Sonja, Montgomery Grant W, Palmer Lyle J, Kalaydjieva Luba, Jablensky Assen
Abstract excerpt
In a previous study we identified a relatively homogeneous subtype of schizophrenia characterized by pervasive cognitive deficit, which was the exclusive contributor to our findings of linkage to 6p25-p24. The 6p region contains Dysbindin (DTNBP1), considered to be one of the major schizophrenia...
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