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Article

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.

American journal of human genetics - 1 Nov 2006

Mutsuddi Mousumi, Morris Derek W, Waggoner Skye G, Daly Mark J, Scolnick Edward M, Sklar Pamela

Abstract excerpt

DTNBP1 was first identified as a putative schizophrenia-susceptibility gene in Irish pedigrees, with a report of association to common genetic variation. Several replication studies have reported confirmation of an association to DTNBP1 in independent European samples; however, reported risk alle...

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Identifiers

PMID: 17033966
DOI: 10.1086/508942
PMCID: PMC1698571

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17033966-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.PMID 17033966Read ↗

Comprehensive analysis of tagging sequence variants in DTNBP1 shows no association with schizophrenia or with its composite neurocognitive endophenotypes.Semantic proximity Read ↗

Analysis of HapMap tag-SNPs in dysbindin (DTNBP1) reveals evidence of consistent association with schizophrenia.Semantic proximity Read ↗

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.Semantic proximity Read ↗

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.Semantic proximity Read ↗

Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?Semantic proximity Read ↗

No evidence for association of the dysbindin gene [DTNBP1] with schizophrenia in an Irish population-based study.Semantic proximity Read ↗

The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease.Semantic proximity Read ↗

Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (DTNBP1) gene in the Irish study of high-density schizophrenia families.Semantic proximity Read ↗

Association study of DTNBP1 with schizophrenia in a US sample.Semantic proximity Read ↗

Identifying potential risk haplotypes for schizophrenia at the DTNBP1 locus in Han Chinese and Scottish populations.Semantic proximity Read ↗

The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample.Semantic proximity Read ↗

Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).Semantic proximity Read ↗

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