Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.

Human molecular genetics - 15 Jul 2005

Bray Nicholas J, Preece Anna, Williams Nigel M, Moskvina Valentina, Buckland Paul R, Owen Michael J, O'Donovan Michael C

Abstract excerpt

The DTNBP1 gene, encoding dysbindin, is now generally considered to be a susceptibility gene for schizophrenia. However, the confidence with which this hypothesis can be held has to be tempered by the poor reproducibility between studies in terms of the exact nature of the associated haplotypes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Carrier Proteins
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dysbindin

Share to Dystrophin-Associated Proteins

Share to Haplotypes

Share to Risk Factors

Share to Schizophrenia

Source

Identifiers

PMID: 15917270
DOI: 10.1093/hmg/ddi199

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15917270-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.PMID 15917270Read ↗

Analysis of HapMap tag-SNPs in dysbindin (DTNBP1) reveals evidence of consistent association with schizophrenia.Semantic proximity Read ↗

Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).Semantic proximity Read ↗

Association study of the dystrobrevin-binding gene with schizophrenia in Australian and Indian samples.Semantic proximity Read ↗

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.Semantic proximity Read ↗

DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene.Semantic proximity Read ↗

The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease.Semantic proximity Read ↗

Relationship between a high-risk haplotype in the DTNBP1 (dysbindin) gene and clinical features of schizophrenia.Semantic proximity Read ↗

Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?Semantic proximity Read ↗

The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample.Semantic proximity Read ↗

Identifying potential risk haplotypes for schizophrenia at the DTNBP1 locus in Han Chinese and Scottish populations.Semantic proximity Read ↗

The dystrobrevin-binding protein 1 gene: features and networks.Semantic proximity Read ↗

Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.