Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.

American journal of human genetics - 1 Aug 2002

Straub Richard E, Jiang Yuxin, MacLean Charles J, Ma Yunlong, Webb Bradley T, Myakishev Maxim V, Harris-Kerr Carole, Wormley Brandon, Sadek Hannah, Kadambi Bharat, Cesare Anthony J, Gibberman Avi, Wang Xu, O'Neill F Anthony, Walsh Dermot, Kendler Kenneth S

Abstract excerpt

Prior evidence has supported the existence of multiple susceptibility genes for schizophrenia. Multipoint linkage analysis of the 270 Irish high-density pedigrees that we have studied, as well as results from several other samples, suggest that at least one such gene is located in region 6p24-21. In the present study, family-based association analysis of 36 simple sequence-length-polymorphism markers and of 17...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 6

Share to Dysbindin

Share to Dystrophin-Associated Proteins

Share to Genetic Markers

Share to Haplotypes

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 12098102
DOI: 10.1086/341750
PMCID: PMC379166

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.PMID 12098102Read ↗

The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease.Semantic proximity Read ↗

Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?Semantic proximity Read ↗

Analysis of HapMap tag-SNPs in dysbindin (DTNBP1) reveals evidence of consistent association with schizophrenia.Semantic proximity Read ↗

Association study of the dystrobrevin-binding gene with schizophrenia in Australian and Indian samples.Semantic proximity Read ↗

No evidence for association of the dysbindin gene [DTNBP1] with schizophrenia in an Irish population-based study.Semantic proximity Read ↗

DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene.Semantic proximity Read ↗

The dystrobrevin-binding protein 1 gene: features and networks.Semantic proximity Read ↗

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.Semantic proximity Read ↗

Dysbindin (DTNBP1, 6p22.3) is associated with childhood-onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS).Semantic proximity Read ↗

Association study of the dysbindin (DTNBP1) gene in schizophrenia from the Japanese population.Semantic proximity Read ↗

The dysbindin gene (DTNBP1) and schizophrenia: no support for an association in the Korean population.Semantic proximity Read ↗

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.