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Article

DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells.

Molecular cancer research : MCR - 1 Feb 2008

Mishra Mark V, Bisht Kheem S, Sun Lunching, Muldoon-Jacobs Kristi, Awwad Rania, Kaushal Aradhana, Nguyen Phuongmai, Huang Lei, Pennington J Daniel, Markovina Stephanie, Bradbury C Matthew, Gius David

Abstract excerpt

We have previously shown that hydrogen peroxide-resistant permanent (OC-14) cells are resistant to the cytotoxicity of several exogenous oxidative and anticancer agents including H(2)O(2), etoposide, and cisplatin; and we refer to this process as an oxidative multimodality-resistant phenotype (MM...

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Source

Identifiers

PMID: 18314485
DOI: 10.1158/1541-7786.MCR-07-0373

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-18314485-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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