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Article

Positive correlation between cellular glutathione and acquired cisplatin resistance in human ovarian cancer cells.

Cell biology and toxicology - 1 Oct 1995

Chen G, Hutter K J, Zeller W J

Abstract excerpt

While multiple changes are frequently found to be associated with cisplatin resistance in a variety of tumor cell lines, a cause-effect relationship of these alterations with the resistant phenotype has not been established. In order to identify the resistance-relevant determinants, a series of c...

Topics

Cell Division
Cisplatin
Cytogenetics
Drug Resistance, Neoplasm
Female
Glutathione
Humans
Ovarian Neoplasms
Phenotype
Poly(ADP-ribose) Polymerases
Sensitivity and Specificity
Tumor Cells, Cultured

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Identifiers

PMID: 8608408
DOI: 10.1007/BF00757625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8608408-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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