Article
Functional diversity of HIV-1 envelope proteins expressed by contemporaneous plasma viruses.
Retrovirology - 29 Feb 2008
Nora Tamara, Bouchonnet Francine, Labrosse Béatrice, Charpentier Charlotte, Mammano Fabrizio, Clavel François, Hance Allan J
Abstract excerpt
BACKGROUND: Numerous studies have shown that viral quasi-species with genetically diverse envelope proteins (Env) replicate simultaneously in patients infected with the human immunodeficiency virus type 1 (HIV-1). Less information is available concerning the extent that envelope sequence diversity translates into a diversity of phenotypic properties, including infectivity and resistance to entry inhibitors....
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