Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration.

The Journal of general virology - 1 Jun 2005

Prechtel Alexander T, Turza Nadine M, Kobelt Dieter J, Eisemann Jutta I, Coffin Robert S, McGrath Yvonne, Hacker Christine, Ju Xinsheng, Zenke Martin, Steinkasserer Alexander

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) is able to establish latency in infected individuals. In order to characterize potential new immune-escape mechanisms, mature dendritic cells (DCs) were infected with HSV-1 and total cellular RNA was isolated from infected and mock-infected populations at different time points. RNA profiling on Affymetrix Human Genome U133A arrays demonstrated a dramatic downregulation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dendritic Cells
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Herpes Simplex

Share to Herpesvirus 1, Human

Share to Receptors, CCR7

Share to Receptors, Chemokine

Share to Receptors, CXCR4

Share to Ribonucleases

Source

Identifiers

PMID: 15914842
DOI: 10.1099/vir.0.80852-0

Genes

CCR7
CXCR4
CCL19
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration.PMID 15914842Read ↗

Herpes simplex virus interference with immunity: Focus on dendritic cellsSemantic proximity Read ↗

Characterization of the Immunologic Phenotype of Dendritic Cells Infected With Herpes Simplex Virus 1.Semantic proximity Read ↗

HIV-1 matrix protein p17 induces human plasmacytoid dendritic cells to acquire a migratory immature cell phenotype.Semantic proximity Read ↗

Mature dendritic cells infected with herpes simplex virus type 1 exhibit inhibited T-cell stimulatory capacity.Semantic proximity Read ↗

An effector phenotype of CD8+ T cells at the junction epithelium during clinical quiescence of herpes simplex virus 2 infection.Semantic proximity Read ↗

The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells.Semantic proximity Read ↗

Antagonizing Viral MicroRNAs Reduces Ocular HSV-1 Pathogenesis and Enhances Mucosal Immune HomeostasisSemantic proximity Read ↗

The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells.Semantic proximity Read ↗

Herpes simplex virus 1 interferes with autophagy of murine dendritic cells and impairs their ability to stimulate CD8+ T lymphocytesSemantic proximity Read ↗

Suppression of Langerhans cell activation is conserved amongst human papillomavirus α and β genotypes, but not a µ genotype.Semantic proximity Read ↗

Functional interaction between herpes simplex virus type 2 gD and HVEM transiently dampens local chemokine production after murine mucosal infection.Semantic proximity Read ↗

Breaching the Barrier: Investigating Initial Herpes Simplex Viral Infection and Spread in Human Skin and MucosaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.