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Article

Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration.

The British journal of ophthalmology - 1 Apr 2008

Goverdhan S V, Ennis S, Hannan S R, Madhusudhana K C, Cree A J, Luff A J, Lotery A J

Abstract excerpt

BACKGROUND/AIMS: To determine whether four expression-related cytokine polymorphisms are associated with age-related macular degeneration (AMD). METHODS: DNA from 478 cases with AMD and 555 normal controls was genotyped for the pro-inflammatory IL1beta -511C/T, IL6 -174C/G, IL8 -251A/T and anti-inflammatory IL10 -1082G/A cytokine polymorphisms using the 5' nuclease TaqMan(R) assay for allelic discrimination....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18310311
DOI: 10.1136/bjo.2007.123190
PMCID: PMC5993190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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