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Article

Translational research goes both ways: lessons from clinical studies.

Clinical and experimental pharmacology & physiology - 1 Apr 2008

Funder John W

Abstract excerpt

1. It is currently assumed that translational research goes from benchtop to bedside; that aldosterone elevates blood pressure via its effects on salt and water homeostasis; that mineralocorticoid receptors (MR) and glucocorticoid receptors (GR) share a common immediate ancestor; and that aldosterone plays a deleterious role in essential hypertension and heart failure. 2. Meta-analysis of clinical trials in...

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Source

Identifiers

PMID: 18307755
DOI: 10.1111/j.1440-1681.2008.04910.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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