Article
Mechanisms of epithelial translocation of the α<sub>2</sub>-gliadin-33mer in coeliac sprue
27 Feb 2008
Abstract excerpt
BACKGROUND AND AIMS: The alpha(2)-gliadin-33mer has been shown to be important in the pathogenesis of coeliac disease. We aimed to study mechanisms of its epithelial translocation and processing in respect to transcytotic and paracellular pathways. METHODS: Transepithelial passage of a fluorescence-labelled alpha(2)-gliadin-33mer was studied in Caco-2 cells by using reverse-phase high-performance liquid...
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