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Article

Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac patients.

Gastroenterology - 1 May 1996

Maiuri L, Picarelli A, Boirivant M, Coletta S, Mazzilli M C, De Vincenzi M, Londei M, Auricchio S

Abstract excerpt

BACKGROUND & AIMS: Mucosal cell-mediated immune response is considered the central event in the pathogenesis of celiac disease. In cultured intestinal explants from celiacs in remission, we have characterized the early stages of gliadin-induced immune activation. METHODS: Intestinal biopsy specimens (15 treated celiacs and 13 controls) were cultured with gliadin or maize prolamine digests for 24 hours as well as...

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PMID: 8613040
DOI: 10.1053/gast.1996.v110.pm8613040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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