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Article

Nitric oxide induces early viral transcription coincident with increased DNA damage and mutation rates in human papillomavirus-infected cells.

Cancer research - 1 Jun 2009

Wei Lanlan, Gravitt Patti E, Song Hebin, Maldonado Anastacia M, Ozbun Michelle A

Abstract excerpt

High-risk human papillomavirus (HPV) infections are necessary but insufficient causes of cervical cancers. Other risk factors for cervical cancer (e.g., pregnancy, smoking, infections causing inflammation) can lead to high and sustained nitric oxide (NO) concentrations in the cervix, and high NO levels are related to carcinogenesis through DNA damage and mutation. However, the effects of NO exposure in...

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Identifiers

PMID: 19487298
DOI: 10.1158/0008-5472.CAN-08-4695
PMCID: PMC3820841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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