Article
High levels of inflammatory biomarkers are associated with increased allele-specific apolipoprotein(a) levels in African-Americans.
The Journal of clinical endocrinology and metabolism - 1 Apr 2008
Anuurad Erdembileg, Rubin Jill, Chiem Alan, Tracy Russell P, Pearson Thomas A, Berglund Lars
Abstract excerpt
BACKGROUND: A role of inflammation for cardiovascular disease (CVD) is established. Lipoprotein(a) [Lp(a)] is an independent CVD risk factor where plasma levels are determined by the apolipoprotein(a) [apo(a)] gene, which contains inflammatory response elements. DESIGN: We investigated the effect of inflammation on allele-specific apo(a) levels in African-Americans and Caucasians. We determined Lp(a) levels,...
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