Comparative analysis of the apo(a) gene, apo(a) glycoprotein, and plasma concentrations of Lp(a) in three ethnic groups. Evidence for no common "null" allele at the apo(a) locus.

Abstract excerpt

Distributions of plasma lipoprotein(a) (Lp[a]) concentrations exhibit marked interracial differences. Apolipoprotein(a) (apo[a]), the unique constituent of Lp(a), is highly polymorphic in length due to allelic variations in the number of kringle 4(K-4)-encoding sequences. Plasma Lp(a) concentrati...

Topics

• Alleles
• Apolipoproteins
• Apoprotein(a)
• Asian People
• Black People
• China
• Chromosome Mapping
• Female
• Glycoproteins
• Humans
• Lipoprotein(a)
• Male