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Article

Apolipoprotein [a] genotype influences isoform dominance pattern differently in African Americans and Caucasians.

Journal of lipid research - 1 Feb 2002

Rubin Jill, Paultre Furcy, Tuck Catherine H, Holleran Steve, Reed Roberta G, Pearson Thomas A, Thomas Christopher M, Ramakrishnan Rajasekhar, Berglund Lars

Abstract excerpt

Plasma lipoprotein [a] (Lp[a]) concentrations are inversely associated with, and largely determined by, apolipoprotein [a] (apo[a]) gene size, a highly polymorphic trait. We studied if, within an individual, the smaller apo[a] isoform always dominated, whether there was interaction between the two alleles, and whether these features differed between Caucasians and African Americans. We determined apo[a] gene...

Topics

Aged
Apolipoproteins A
Black People
Female
Gene Frequency
Genes, Dominant
Genotype
Humans
Lipoprotein(a)
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Isoforms

White People

Black or African American

Source

Identifiers

PMID: 11861665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11861665-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Apolipoprotein [a] genotype influences isoform dominance pattern differently in African Americans and Caucasians.PMID 11861665Read ↗

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