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Article

Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial.

Pharmacogenomics - 1 Mar 2008

Lavedan Christian, Volpi Simona, Polymeropoulos Mihael H, Wolfgang Curt D

Abstract excerpt

AIMS: Presence of the null FS63TER allele of the rs1800169 polymorphism in the gene encoding the ciliary neurotrophic factor (CNTF) may increase the risk of schizophrenia. This study prospectively evaluated the CNTF rs1800169 genotype (G/G vs non-G/G) effects on response to iloperidone. PATIENTS & METHODS: Iloperidone 24 mg/day was evaluated in a study of patients with schizophrenia. Efficacy measurements...

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Identifiers

PMID: 18303965
DOI: 10.2217/14622416.9.3.289

Genes

CNTF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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