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Article

Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia.

Molecular psychiatry - 1 Nov 2009

Volpi S, Heaton C, Mack K, Hamilton J B, Lannan R, Wolfgang C D, Licamele L, Polymeropoulos M H, Lavedan C

Abstract excerpt

Administration of certain drugs (for example, antiarrhythmics, antihistamines, antibiotics, antipsychotics) may occasionally affect myocardial repolarization and cause prolongation of the QT interval. We performed a whole genome association study of drug-induced QT prolongation after 14 days of treatment in a phase 3 clinical trial evaluating the efficacy, safety and tolerability of a novel atypical...

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Source

Identifiers

PMID: 18521091
DOI: 10.1038/mp.2008.52

Genes

CERKL
NRG3
PALLD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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